Chemically defined conditions for human iPSC derivation and culture

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Nature Methods

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Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells

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Cell

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Efficient genome engineering in human pluripotent stem cells using Cas9 from <i>Neisseria meningitidis</i>

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Proceedings of the National Academy of Sciences

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Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease

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Journal of Clinical Investigation

Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease

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Neuron

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Human pluripotent stem cell-derived neural constructs for predicting neural toxicity

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Proceedings of the National Academy of Sciences

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Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease

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Science Translational Medicine

Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging

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Journal of Clinical Investigation

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

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Nature Neuroscience

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Immunity

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