Integrative analysis of 111 reference human epigenomes

Anshul Kundaje, Wouter Meuleman, Jason Ernst, +91

Nature

BioinformaticsChromatinGenome-wide Association StudyMedicineGenetics +12

Chromatin architecture reorganization during stem cell differentiation

Jesse R. Dixon, Inkyung Jung, Siddarth Selvaraj, +14

Nature

Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution

Nimet Maherali, Rupa Sridharan, Wei Xie, +9

Cell stem cell

ChromatinDevelopmental BiologyCardiac ReprogrammingWidespread Tissue ContributionChromatin Remodeling +9

Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures

Mark H. Chin, Mike J. Mason, Wei Xie, +20

Cell stem cell

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Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells

Wei Xie, Matthew D. Schultz, Ryan Lister, +39

Cell

ChromatinCell LineageDevelopmental BiologyCell SpecializationMedicine +10

The landscape of accessible chromatin in mammalian preimplantation embryos

Jingyi Wu, Bo Huang, He Chen, +21

Nature

ChromatinDevelopmental BiologyChromatin RemodelingGeneticsPreimplantation Genetic Testing +5

Allelic reprogramming of the histone modification H3K4me3 in early mammalian development

Bingjie Zhang, Hui Zheng, Bo Huang, +23

Nature

Histone ModificationsChromatinEarly Mammalian DevelopmentHistone Modification H3k4me3Developmental Biology +12

Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes

Hao Wu, Volkan Coskun, Jifang Tao, +6

Science

Total Synthesis of a Functional Designer Eukaryotic Chromosome

Narayana Annaluru, Héloïse Muller, Leslie A. Mitchell, +77

Science

Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome

Wei Xie, Cathy L. Barr, Audrey Kim, +5

Cell