Concepedia

Protein Design

Protein Design is the computational or experimental discipline within protein engineering and structural bioinformatics that involves the creation of novel amino acid sequences or structural configurations to achieve specified biological functions or stability characteristics, distinguished from related fields by its focus on de novo prediction and optimization rather than analysis of naturally occurring proteins.

7.2K

Publications

506.2K

Citations

29.8K

Authors

4K

Institutions

Publications per year

2017–2026

2.5K

Parents

Children

Publications

7.2K

Accurate structure prediction of biomolecular interactions with AlphaFold 3

Josh Abramson, Jonas Adler, Jack Dunger et al. · Nature · 2024 · 13.8K citations · Full text

, , +12

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

Andrew C. Wallace, Roman A. Laskowski, Janet M. Thornton · Protein Engineering Design and Selection · 1995 · 5.7K citations

, , +14

Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation

Kathleen M. Sakamoto, Kyung B. Kim, Akiko Kumagai et al. · Proceedings of the National Academy of Sciences · 2001 · 2.5K citations · Full text

, , +16

Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor

Fang Li, Wenhui Li, Michael Farzan et al. · Science · 2005 · 2.2K citations

, , +17

Protein structure prediction and analysis using the Robetta server

David E. Kim, Dylan Chivian, David Baker · Nucleic Acids Research · 2004 · 2.2K citations · Full text

, , +17

1–5 of 7.2K

Authors

29.8K

  1. DB
    David Baker

    University of Washington, United States

    218 publications · 40.9K citations

    95

    h-index

  2. WF
    William F. DeGrado

    University of Pennsylvania, United States

    64 publications · 8.3K citations

    45

    h-index

  3. BK
    Brian Kuhlman

    University of North Carolina at Chapel Hill, United States

    56 publications · 9.2K citations

    38

    h-index

  4. SL
    Stephen L. Mayo

    California Institute of Technology, United States

    46 publications · 5.9K citations

    36

    h-index

  5. AP
    Andreas Plückthun

    University of Zurich, Switzerland

    57 publications · 5.2K citations

    35

    h-index

1–5 of 29.8K

Institutions

4K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    115 h-index

    626 publications

    148.4K citations

  2. University of Washington

    Seattle, United States

    105 h-index

    2.1K publications

    386.4K citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    63 h-index

    493 publications

    49.6K citations

  4. University of California, San Francisco

    San Francisco, United States

    61 h-index

    457 publications

    50.1K citations

  5. Harvard University

    Cambridge, United States

    60 h-index

    406 publications

    54.8K citations

  6. California Institute of Technology

    Pasadena, United States

    58 h-index

    332 publications

    35.3K citations

  7. University of Pennsylvania

    Philadelphia, United States

    56 h-index

    541 publications

    50.4K citations

  8. Scripps Research Institute

    San Diego, United States

    56 h-index

    446 publications

    49.9K citations

1–8 of 4K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 330 publications · 49.1K citations

    119

    h-index

  2. Journal of the American Chemical Society

    JACS · 368 publications · 26.7K citations

    90

    h-index

  3. Science

    99 publications · 35.4K citations

    81

    h-index

  4. Journal of Molecular Biology

    JMB · 205 publications · 18.1K citations

    78

    h-index

  5. Protein Engineering Design and Selection

    PEDS · 293 publications · 24.5K citations

    70

    h-index

1–5