Concepedia

Generative Protein Design

Generative Protein Design is a computational approach within protein engineering that, as a distinct paradigm under the broader field of protein design modeling, employs generative algorithms to create novel protein sequences or structures by learning underlying patterns and physical principles from existing protein data.

64

Publications

5.8K

Citations

285

Authors

81

Institutions

Publications per year

2017–2026

62

Parents

Publications

64

ProtGPT2 is a deep unsupervised language model for protein design

Noelia Ferruz, Steffen Schmidt, Birte Höcker · Nature Communications · 2022 · 776 citations · Full text

, , +14

Illuminating protein space with a programmable generative model

John Ingraham, Max Baranov, Zak Costello et al. · Nature · 2023 · 403 citations · Full text

, , +17

An evolution-based model for designing chorismate mutase enzymes

William P. Russ, Matteo Figliuzzi, Christian Stocker et al. · Science · 2020 · 362 citations

, , +17

Protein design and variant prediction using autoregressive generative models

Jung-Eun Shin, Adam J. Riesselman, Aaron W. Kollasch et al. · Nature Communications · 2021 · 350 citations · Full text

, , +13

Hallucinating symmetric protein assemblies

Basile I. M. Wicky, Lukas F. Milles, Alexis Courbet et al. · Science · 2022 · 255 citations · Full text

, , +17

1–5 of 64

Authors

285

  1. PH
    Po‐Ssu Huang

    Stanford University, United States

    7 publications · 543 citations

    7

    h-index

  2. MJ
    Markus J. Buehler

    Massachusetts Institute of Technology, United States

    6 publications · 238 citations

    6

    h-index

  3. RR
    Raphael R. Eguchi

    Stanford University, United States

    5 publications · 461 citations

    5

    h-index

  4. AM
    Ali Madani

    Salesforce (United States), United States

    4 publications · 343 citations

    4

    h-index

  5. BH
    Birte Höcker

    University of Bayreuth, Germany

    3 publications · 990 citations

    3

    h-index

1–5 of 285

Institutions

81

  1. Massachusetts Institute of Technology

    Cambridge, United States

    10 h-index

    23 publications

    1.7K citations

  2. Stanford University

    Stanford, United States

    9 h-index

    27 publications

    2.4K citations

  3. University of Toronto

    Toronto, Canada

    4 h-index

    9 publications

    355 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    5 publications

    745 citations

  5. University of Chicago

    Chicago, United States

    4 h-index

    9 publications

    818 citations

  6. University of Washington

    Seattle, United States

    4 h-index

    45 publications

    5.8K citations

  7. Sorbonne Université

    Paris, France

    3 h-index

    9 publications

    1.5K citations

  8. University of Bayreuth

    Bayreuth, Germany

    3 h-index

    8 publications

    2.8K citations

1–8 of 81

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 20 publications · 1K citations

    17

    h-index

  2. arXiv (Cornell University)

    Repository · 9 publications · 353 citations

    9

    h-index

  3. Nature Communications

    5 publications · 1.3K citations

    5

    h-index

  4. Science

    3 publications · 690 citations

    3

    h-index

  5. Nature Machine Intelligence

    3 publications · 480 citations

    3

    h-index

1–5