Zak Costello

Illuminating protein space with a programmable generative model

John Ingraham, Max Baranov, Zak Costello et al. · Nature · 2023 · 403 citations · Full text

Life Sciences, Bioinformatics, Materials Science +17

Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism

Jie Zhang, Søren D. Petersen, Tijana Radivojević et al. · Nature Communications · 2020 · 277 citations · Full text

Engineering, Bioengineering, Biotechnology +17

A machine learning approach to predict metabolic pathway dynamics from time-series multiomics data

Zak Costello, Héctor García Martín · npj Systems Biology and Applications · 2018 · 250 citations · Full text

Engineering, Bioengineering, Biological Engineering +12

Industrial brewing yeast engineered for the production of primary flavor determinants in hopped beer

Charles M. Denby, Rachel A. Li, Van Tien Vu et al. · Nature Communications · 2018 · 221 citations · Full text

Engineering, Bioengineering, Biotechnology +17

Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in <i>Escherichia coli</i> Aided by Machine Learning

Paul H. Opgenorth, Zak Costello, Takuya Okada et al. · ACS Synthetic Biology · 2019 · 162 citations · Full text

Engineering, Bioengineering, Biotechnology +17