Concepedia

Binding Protein Design

Binding Protein Design is a protein design methodology that specifically involves the creation of proteins engineered to interact with high affinity and selectivity with a target molecule, distinguishing it from other protein design approaches by its focus on molecular recognition and complex formation.

31

Publications

2.8K

Citations

262

Authors

70

Institutions

Publications per year

2017–2026

12

Parents

Publications

31

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

Sarel J. Fleishman, Timothy A. Whitehead, Damian C. Ekiert et al. · Science · 2011 · 597 citations

, , +17

Improving de novo protein binder design with deep learning

Nathaniel R. Bennett, Brian Coventry, Inna Goreshnik et al. · Nature Communications · 2023 · 359 citations · Full text

, , +17

Minimizing a binding domain from protein A.

Andrew C. Braisted, James A. Wells · Proceedings of the National Academy of Sciences · 1996 · 306 citations

, , +17

Engineering of a femtomolar affinity binding protein to human serum albumin

Anders Jönsson, Jakob Dogan, Nina Herne et al. · Protein Engineering Design and Selection · 2008 · 228 citations · Full text

, , +17

A defined structural unit enables de novo design of small-molecule–binding proteins

Nicholas F. Polizzi, William F. DeGrado · Science · 2020 · 152 citations · Full text

, , +16

1–5 of 31

Authors

262

  1. DB
    David Baker

    University of Washington, United States

    5 publications · 1.2K citations

    5

    h-index

  2. NR
    Nathaniel R. Bennett

    University of Washington, United States

    2 publications · 381 citations

    2

    h-index

  3. ES
    Eva‐Maria Strauch

    University of Washington, United States

    2 publications · 689 citations

    2

    h-index

  4. JW
    Jason W. Chin

    MRC Laboratory of Molecular Biology, United Kingdom

    2 publications · 126 citations

    2

    h-index

  5. BK
    Brian Kuhlman

    University of North Carolina at Chapel Hill, United States

    2 publications · 91 citations

    2

    h-index

1–5 of 262

Institutions

70

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    12 publications

    2.4K citations

  2. University of Washington

    Seattle, United States

    5 h-index

    44 publications

    8.5K citations

  3. University of Lausanne

    Lausanne, Switzerland

    2 h-index

    5 publications

    296 citations

  4. University of Zurich

    Zurich, Switzerland

    2 h-index

    11 publications

    749 citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    9 publications

    480 citations

  6. Yale University

    New Haven, United States

    2 h-index

    4 publications

    252 citations

  7. University at Buffalo, State University of New York

    Buffalo, United States

    2 h-index

    5 publications

    465 citations

  8. PDL BioPharma (United States)

    Incline Village, United States

    2 h-index

    3 publications

    971 citations

1–8 of 70

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 538 citations

    3

    h-index

  2. Angewandte Chemie International Edition

    3 publications · 148 citations

    3

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 131 citations

    2

    h-index

  4. ChemBioChem

    2 publications · 87 citations

    2

    h-index

  5. Science

    2 publications · 749 citations

    2

    h-index

1–5