Concepedia

James A. Wells

JA

256

Publications

37.3K

Citations

101

H-Index

1939

Active since

Affiliations

University of California, San Francisco(Current)

PDL BioPharma (United States)

Sunesis (United States)

Chan Zuckerberg Initiative (United States)

Howard Hughes Medical Institute

James A. Wells is an author at University of California, San Francisco specializing in medicine, natural sciences, and biochemistry.

Top concepts

MedicineNatural SciencesBiochemistryMolecular BiologyProteomicsProtein EngineeringProtein FoldingCell BiologySignal TransductionBiomolecular Engineering

Publications per year

1939–2025

256

Publications

256

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

J.M. Ostrem, Ulf Peters, Martin L. Sos et al. · Nature · 2013 · 2.4K citations · Full text

Molecular Pharmacology, Signal Transduction, G Protein-coupled Receptor +7

A Hot Spot of Binding Energy in a Hormone-Receptor Interface

Tim Clackson, James A. Wells · Science · 1995 · 2K citations

Contact Residues, Protein Assembly, Human Growth +19

High-Resolution Epitope Mapping of hGH-Receptor Interactions by Alanine-Scanning Mutagenesis

Brian C. Cunningham, James A. Wells · Science · 1989 · 1.4K citations

Dimerization of the Extracellular Domain of the Human Growth Hormone Receptor by a Single Hormone Molecule

Brian C. Cunningham, Mark Ultsch, Abraham M. de Vos et al. · Science · 1991 · 885 citations

Single Hormone Molecule, Developmental Biology, Signal Transduction +15

Sexually Dimorphic Neurons in the Ventromedial Hypothalamus Govern Mating in Both Sexes and Aggression in Males

Cindy F. Yang, Michael C. Chiang, Daniel C. Gray et al. · Cell · 2013 · 706 citations · Full text

Behavioral Sciences, Both Sexes, Behavioral Neuroscience +15

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