Mark Ultsch

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

Abraham M. de Vos, Mark Ultsch, Anthony A. Kossiakoff · Science · 1992 · 2.2K citations

Crystal Structure, Human Growth, Extracellular Domain +17

Dimerization of the Extracellular Domain of the Human Growth Hormone Receptor by a Single Hormone Molecule

Brian C. Cunningham, Mark Ultsch, Abraham M. de Vos et al. · Science · 1991 · 885 citations

Single Hormone Molecule, Developmental Biology, Signal Transduction +15

The Identification of 2-(1<i>H</i>-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-<i>d</i>]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer

Adrian Folkes, Khatereh Ahmadi, W. Alderton et al. · Journal of Medicinal Chemistry · 2008 · 739 citations · Full text

Pi3 Kinase, Chemoprevention Strategy, Pharmacotherapy +18

Convergent Solutions to Binding at a Protein-Protein Interface

Warren L. DeLano, Mark Ultsch, Abraham M. de et al. · Science · 2000 · 679 citations

Crystal Structure, Protein Assembly, Peptide Engineering +16

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

Honglin Zhou, Ingrid E. Wertz, Karen O’Rourke et al. · Nature · 2003 · 524 citations

Signal Transduction, Signaling Pathway, Cell Regulation +5