Ingrid E. Wertz

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

Ingrid E. Wertz, Karen O’Rourke, Honglin Zhou et al. · Nature · 2004 · 1.8K citations

Signal Transduction, Cell Regulation, Molecular Pathway +11

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Ingrid E. Wertz, Saritha Kusam, Cynthia Lam et al. · Nature · 2011 · 806 citations

Protein Function, Medicine, Immune Checkpoint Inhibitor +9

The ubiquitin ligase COP1 is a critical negative regulator of p53

David Dornan, Ingrid E. Wertz, Harumi Shimizu et al. · Nature · 2004 · 701 citations

Cell Regulation, Molecular Regulation, Critical Negative Regulator +7

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

Qing Zhou, Hongying Wang, Daniella M. Schwartz et al. · Nature Genetics · 2015 · 601 citations · Full text

Inflammation, Rheumatology, A20 Haploinsufficiency Cause +14

Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies

Kim Newton, M Matsumoto, Ingrid E. Wertz et al. · Cell · 2008 · 550 citations · Full text

Ubiquitin Chain Editing, Autoimmune Disease, Immunology +4