Concepedia

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

Qing Zhou, Hongying Wang, Daniella M. Schwartz, Monique Stoffels, Yong Hwan Park, Yuan Zhang, Dan Yang, Erkan Demirkaya, Masaki Takeuchi, Wanxia Li Tsai,

Nature Genetics · 2015 · 633 citations · 33 references

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33

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae et al. · Nature Medicine · 2015 · 2.8K citations · Full text

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

Ingrid E. Wertz, Karen O’Rourke, Honglin Zhou et al. · Nature · 2004 · 1.8K citations

, , +12

Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice

Eric G. Lee, David L. Boone, Sophia Chai et al. · Science · 2000 · 1.4K citations · Full text

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

Rajan P. Nair, Kristina Callis Duffin, Cynthia Helms et al. · Nature Genetics · 2009 · 1.4K citations · Full text

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The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

Geun‐Shik Lee, Naeha Subramanian, Andrew I. Kim et al. · Nature · 2012 · 1.1K citations

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