Concepedia

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

Geun‐Shik Lee, Naeha Subramanian, Andrew I. Kim, Ivona Aksentijevich, Raphaela Goldbach‐Mansky, David B. Sacks, Ronald N. Germain, Daniel L. Kastner, Jae Jin Chae

Nature · 2012 · 1.1K citations · 20 references

DOI

Concepts

References

20

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.9K citations · Full text

, , +12

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

, , +13

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Rongbin Zhou, Aubry Tardivel, Bernard Thorens et al. · Nature Immunology · 2009 · 2.7K citations

, , +12

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

Bolormaa Vandanmagsar, Yun‐Hee Youm, Anthony Ravussin et al. · Nature Medicine · 2011 · 2.6K citations · Full text

, , +14