Cholesterol-Lowering Effects of Rice Bran and Rice Bran Oil Fractions in Hypercholesterolemic Hamsters

Abstract

Cereal Chem. 69(5):485-489 The effects of temperature of extraction and fractionation of rice bran significantly lower plasma and liver cholesterol and triglycerides were oil were evaluated alone or in combination with defatted rice bran (DFB) observed in those fed an FFB diet than in those fed a CC diet. A diet to determine the effects on their cholesterol-lowering potential in hyper- consisting of DFB in combination with degummed-dewaxed rice bran cholesterolemic hamsters. Diets containing full-fat rice bran (FFB), DFB oil resulted in significantly lower liver cholesterol levels than did the CC plus rice bran oil (extracted at 4 or 540C), and 540C-extracted rice bran diet, whereas DFB alone, rice bran oil extracted at either temperature, oil fractions (gum, wax, and degummed-dewaxed oil) at levels found or DFB plus gum or wax fractions were not significantly different from in FFB were fed to 23-day-old hamsters. All diets contained 10% total the respective corn oil controls. Only FFB lowered both plasma and dietary fiber, 9% fat, and 3% nitrogen. After 21 days, liver weights and liver cholesterol in hamsters. The data suggest that some of the cholesterolplasma and liver cholesterol and plasma triglycerides were significantly lowering properties of FFB are present when DFB is recombined with higher in animals fed a diet of 0.3% cholesterol with cellulose (CC) than degummed-dewaxed rice bran oil, but some active components appear in animals fed a cholesterol-free cellulose diet. In cholesterol-fed hamsters, to be either lost or are deactivated in the fractionation process.