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Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

Protein FunctionSignal TransductionBiochemistryG Protein-coupled ReceptorNatural SciencesMedicinePharmacologyChemical ModificationProtein PhosphorylationBiochemical InteractionProtein EngineeringCellular BiochemistryTherapeutic IndexProteomicsPs-aso TherapeuticsDrug Discovery