Timothy A. Vickers

Antisense Masking of an hnRNP A1/A2 Intronic Splicing Silencer Corrects SMN2 Splicing in Transgenic Mice

Yimin Hua, Timothy A. Vickers, Hazeem L. Okunola et al. · The American Journal of Human Genetics · 2008 · 558 citations · Full text

Antisense Masking, Knockout Mouse, Transcriptional Regulation +9

Efficient Reduction of Target RNAs by Small Interfering RNA and RNase H-dependent Antisense Agents

Timothy A. Vickers, Seongjoon Koo, C. Frank Bennett et al. · Journal of Biological Chemistry · 2003 · 458 citations · Full text

Enhancement of SMN2 Exon 7 Inclusion by Antisense Oligonucleotides Targeting the Exon

Yimin Hua, Timothy A. Vickers, Brenda F. Baker et al. · PLoS Biology · 2007 · 334 citations · Full text

Rna Processing, Exon Skipping, Systems Biology +15

Phosphorothioate modified oligonucleotide–protein interactions

Stanley T. Crooke, Timothy A. Vickers, Xue‐hai Liang · Nucleic Acids Research · 2020 · 318 citations · Full text

Nucleic Acid Chemistry, Biochemistry, Aso Chemical Modifications +13

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

Wen Shen, Cheryl Li De Hoyos, Michael T. Migawa et al. · Nature Biotechnology · 2019 · 308 citations

Protein Function, Signal Transduction, Biochemistry +13