Xue‐hai Liang - Concepedia

Author

Xue‐hai Liang

Ionis Pharmaceuticals (United States)ORCID

Also Known As

LIANG Xue-Hai, Liang X, Liang Xuehai, X. Liang, XUE-HAI LIANG, Xue-Hai Liang, Xue-hai Liang, Xuehai Liang, Xue‐hai Liang

103

Publications

7.4K

Citations

H-Index

Concepts

All Affiliations

Ionis Pharmaceuticals (United States)Bar-Ilan University University of Georgia University of Massachusetts Amherst

About

Xue‐hai Liang is an author at Ionis Pharmaceuticals (United States) specializing in molecular biology, natural sciences, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	28	33	3K
2	Medicine	27	34	2.5K
3	Engineering	12	14	678
4	Biochemistry	12	13	1.4K
5	Applied Physics	4	4	138

Xue‐hai Liang

Publications

5.2K

Citations

H-Index

Page 1

	Year	Citations
Phosphorothioate modified oligonucleotide–protein interactions Stanley T. Crooke, Timothy A. Vickers, Xue‐hai Liang Nucleic Acids Research Nucleic Acid ChemistryBiochemistryAso Chemical ModificationsNatural SciencesMedicine	2020	318
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index Wen Shen, Cheryl Li De Hoyos, Michael T. Migawa, Nature Biotechnology Protein FunctionSignal TransductionBiochemistryG Protein-coupled ReceptorNatural Sciences	2019	308
RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus Xue‐hai Liang, Hong Sun, Joshua G Nichols, Molecular Therapy	2017	268
Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processing Xue‐hai Liang, Qing Liu, Maurille J. Fournier RNA	2009	235
rRNA Modifications in an Intersubunit Bridge of the Ribosome Strongly Affect Both Ribosome Biogenesis and Activity Xue‐hai Liang, Qing Liu, Maurille J. Fournier Molecular Cell Intersubunit BridgeSystems BiologyEngineeringNatural SciencesRrna Modifications	2007	220
Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames Xue‐hai Liang, Wen‐Hui Shen, Hong Sun, Nature Biotechnology Natural SciencesRna Structure PredictionRna BiologyDna ReplicationMolecular Biology	2016	203
Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages Xue‐hai Liang, Hong Sun, Wen Shen, Nucleic Acids Research Protein AssemblyMolecular BiologyProtein FoldingAntisense TherapyProteomics	2015	176
Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracy Agnès Baudin‐Baillieu, Céline Fabret, Xue‐hai Liang, Nucleic Acids Research	2009	152
Antisense oligonucleotides targeting translation inhibitory elements in 5′ UTRs can selectively increase protein levels Xue‐hai Liang, Hong Sun, Wen Shen, Nucleic Acids Research	2017	129
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides Brooke A. Anderson, Graeme C. Freestone, Audrey Low, Nucleic Acids Research Dna GapGene TherapiesNovel TherapyGapmer Ps AsosTherapeutic Index	2021	121

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