Concepedia

Joshua G Nichols

JG

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Publications

10

Citations

725

H-Index

10

Active since

2016

Affiliations

Ionis Pharmaceuticals (United States)(Current)

Joshua G Nichols is an author at Ionis Pharmaceuticals (United States) specializing in life sciences, molecular biology, and antisense rnas.

Publications per year

2016–2022

10

Publications

10

RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus

Xue‐hai Liang, Hong Sun, Joshua G Nichols et al. · Molecular Therapy · 2017 · 283 citations · Full text

, , +16

Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins

Michael T. Migawa, Wen Shen, Guillermo Vasquez et al. · Nucleic Acids Research · 2019 · 124 citations · Full text

, , +14

Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2′-modifications and enhances antisense activity

Xue‐hai Liang, Wen Shen, Hong Sun et al. · Nucleic Acids Research · 2016 · 80 citations · Full text

, , +16

mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway

Xue‐hai Liang, Joshua G Nichols, Chih‐Wei Hsu et al. · Nucleic Acids Research · 2019 · 59 citations · Full text

, , +17

Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomes

Xue‐hai Liang, Hong Sun, Chih‐Wei Hsu et al. · Nucleic Acids Research · 2019 · 46 citations · Full text

, , +17

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