Kasey R. Hutt

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

Magdalini Polymenidou, Clotilde Lagier‐Tourenne, Kasey R. Hutt et al. · Nature Neuroscience · 2011 · 1.3K citations · Full text

Neuronal Vulnerability, Molecular Neuroscience, Medicine +10

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

Clotilde Lagier‐Tourenne, Magdalini Polymenidou, Kasey R. Hutt et al. · Nature Neuroscience · 2012 · 732 citations · Full text

Protein Function, Amyotrophic Lateral Sclerosis, Natural Sciences +9

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

Chunru Lin, Liuqing Yang, Bogdan Tanasă et al. · Cell · 2009 · 569 citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +6

Targeted degradation of sense and antisense <i>C9orf72</i> RNA foci as therapy for ALS and frontotemporal degeneration

Clotilde Lagier‐Tourenne, Michael W. Baughn, Frank Rigo et al. · Proceedings of the National Academy of Sciences · 2013 · 551 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Sporadic Als +13

Histone Methylation-Dependent Mechanisms Impose Ligand Dependency for Gene Activation by Nuclear Receptors

Ivan García-Bassets, Young‐Soo Kwon, Francesca Telese et al. · Cell · 2007 · 432 citations · Full text

Histone Modifications, Chromatin, Chromatin Remodeling +13