Frank Rigo

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

Eric L. Van Nostrand, Gabriel A. Pratt, A.A. Shishkin et al. · Nature Methods · 2016 · 1.5K citations

Enhanced Clip, Functional Genomics, Robust Transcriptome-wide Discovery +12

Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study

Richard S. Finkel, Claudia A. Chiriboga, Jiri Vajsar et al. · The Lancet · 2016 · 998 citations

Dose-escalation Study, Spinal Cord Injury, Pediatric Spine +6

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

Christopher J. Donnelly, Ping‐Wu Zhang, Jacqueline T. Pham et al. · Neuron · 2013 · 875 citations · Full text

Rna Toxicity, Engineering, Rna Biology +8

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

Yimin Hua, Kentaro Sahashi, Frank Rigo et al. · Nature · 2011 · 732 citations · Full text

Regenerative Medicine, Neuroregeneration, Spinal Cord Injury +9

Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a <i>C9ORF72</i> Repeat Expansion

Dhruv Sareen, Jacqueline G. O’Rourke, Pratap Meera et al. · Science Translational Medicine · 2013 · 672 citations · Full text