Concepedia

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

Christopher J. Donnelly, Ping‐Wu Zhang, Jacqueline T. Pham, Aaron R. Haeusler, Nipun A. Mistry, Svetlana Vidensky, Elizabeth L. Daley, Erin M. Poth, Benjamin Hoover, Daniel M. Fines,

Neuron · 2013 · 882 citations · 42 references

DOI

Concepts

References

42

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

Alan E. Renton, Elisa Majounie, Adrian J. Waite et al. · Neuron · 2011 · 4.5K citations · Full text

, , +14

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

John T. Dimos, Kit T. Rodolfa, Kathy K. Niakan et al. · Science · 2008 · 2K citations

, , +17

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

Jeffrey D. Rothstein, Marleen Van Kammen, Allan I. Levey et al. · Annals of Neurology · 1995 · 1.5K citations

, , +15

The <i>C9orf72</i> GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS

Kohji Mori, Shih‐Ming Weng, Thomas Arzberger et al. · Science · 2013 · 1.3K citations

, , +17

Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

Elisa Majounie, Alan E. Renton, Kin Y. Mok et al. · The Lancet Neurology · 2012 · 1.2K citations · Full text

, , +15