Aaron R. Haeusler

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

Ke Zhang, Christopher J. Donnelly, Aaron R. Haeusler et al. · Nature · 2015 · 974 citations

Natural Sciences, Molecular Biology, Dna Replication +6

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

Aaron R. Haeusler, Christopher J. Donnelly, Goran Periz et al. · Nature · 2014 · 969 citations · Full text

Disease Mechanism, Natural Sciences, Molecular Biology +3

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

Christopher J. Donnelly, Ping‐Wu Zhang, Jacqueline T. Pham et al. · Neuron · 2013 · 875 citations · Full text

Rna Toxicity, Engineering, Rna Biology +8

Repeat‐associated non‐ <scp>AUG</scp> translation in C9orf72‐ <scp>ALS</scp> / <scp>FTD</scp> is driven by neuronal excitation and stress

Thomas Westergard, Kevin McAvoy, K. Russell et al. · EMBO Molecular Medicine · 2019 · 120 citations · Full text

G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA

Eric A.J. Simko, Honghe Liu, Tao Zhang et al. · Nucleic Acids Research · 2020 · 93 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +16