Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

Identification and characterization of a spinal muscular atrophy-determining gene

Suzie Lefebvre, Lydie Bürglen, Sophie Reboullet et al. · Cell · 1995 · 3.9K citations · Full text

Genetics, Gene Characterization, Molecular Genetics +3

Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model

Brian K. Kaspar, Jerònia Lladó, Nushin Sherkat et al. · Science · 2003 · 863 citations

Viral Pathogenesis, Immunology, Biomedical Engineering +16

IGF-I is required for normal embryonic growth in mice.

Lyn Powell-Braxton, Philip G. Hollingshead, Corinna Warburton et al. · Genes & Development · 1993 · 806 citations · Full text

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Kevin D. Foust, Xueyong Wang, Vicki L. McGovern et al. · Nature Biotechnology · 2010 · 685 citations · Full text

Knockout Mouse, Early Postnatal Delivery, Spinal Cord Injury +8

Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model

Yimin Hua, Kentaro Sahashi, Gene Hung et al. · Genes & Development · 2010 · 649 citations · Full text

Immunology, Cell Death, Pathology +18