Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

Identification and characterization of a spinal muscular atrophy-determining gene

Suzie Lefebvre, Lydie Bürglen, Sophie Reboullet et al. · Cell · 1995 · 4K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +6

Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model

Brian K. Kaspar, Jerònia Lladó, Nushin Sherkat et al. · Science · 2003 · 867 citations

Life Sciences, Neurology, Neuroscience +17

IGF-I is required for normal embryonic growth in mice.

Lyn Powell-Braxton, Philip G. Hollingshead, Corinna Warburton et al. · Genes & Development · 1993 · 807 citations · Full text

Life Sciences, Developmental Biology, Endocrinology +7

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Kevin D. Foust, Xueyong Wang, Vicki L. McGovern et al. · Nature Biotechnology · 2010 · 690 citations · Full text

Medicine, Neurobiology, Neuroscience +10

Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model

Yimin Hua, Kentaro Sahashi, Gene Hung et al. · Genes & Development · 2010 · 655 citations · Full text

Life Sciences, Neurology, Neuroscience +17