Andrew Siwkowski - Concepedia

Author

Andrew Siwkowski

Ionis Pharmaceuticals (United States)

Also Known As

A. M. Siwkowski, Andrew M. Siwkowski, Andrew Siwkowski

Publications

1.7K

Citations

H-Index

Concepts

All Affiliations

Ionis Pharmaceuticals (United States)Northern Illinois University

About

Andrew Siwkowski is an author at Ionis Pharmaceuticals (United States) specializing in biochemistry, medicine, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	281
2	Biochemistry	5	5	242
3	Natural Sciences	4	4	175
4	Engineering	1	1	11
5	Health Sciences	1	1	35

Andrew Siwkowski

Publications

1.6K

Citations

H-Index

Page 1

	Year	Citations
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals Eric E. Swayze, Andrew Siwkowski, Edward V. Wancewicz, Nucleic Acids Research	2006	450
Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals Punit P. Seth, Andrew Siwkowski, Charles Allerson, Journal of Medicinal Chemistry	2008	263
Inhibition of <i>HPV-16 E6/E7</i> immortalization of normal keratinocytes by hairpin ribozymes Luis Marat Álvarez-Salas, Amy Cullinan, Andrew Siwkowski, Proceedings of the National Academy of Sciences	1998	95
Antisense Oligonucleotide Blockade of Tumor Necrosis Factor-α in Two Murine Models of Colitis Kathleen Myers, Sreekant Murthy, Anne Flanigan, Journal of Pharmacology and Experimental Therapeutics	2003	90
Human RNase H1 Discriminates between Subtle Variations in the Structure of the Heteroduplex Substrate Walt F. Lima, J. Bart Rose, Josh G. Nichols, Molecular Pharmacology	2006	89
An Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNA Punit P. Seth, Charles Allerson, Andrés Berdeja, Journal of the American Chemical Society	2010	85
Effect of dose and plasma concentration on liver uptake and pharmacologic activity of a 2′-methoxyethyl modified chimeric antisense oligonucleotide targeting PTEN Richard S. Geary, Ed Wancewicz, John Matson, Biochemical Pharmacology Pharmacologic ActivityDrug TargetingBiochemistryMedicinePharmacotherapy	2009	82
Antisense Oligonucleotides Containing Conformationally Constrained 2′,4′-(<i>N</i>-Methoxy)aminomethylene and 2′,4′-Aminooxymethylene and 2′-<i>O</i>,4′-<i>C</i>-Aminomethylene Bridged Nucleoside Analogues Show Improved Potency in Animal Models Thazha P. Prakash, Andrew Siwkowski, Charles Allerson, Journal of Medicinal Chemistry Bioorganic ChemistryMolecular BiologyMoe ModificationChemical BiologyPharmaceutical Chemistry	2010	72
Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing Andrew Siwkowski Nucleic Acids Research Adaptive Immune SystemImmunologyImmune RegulationMolecular BiologyImmunologic Mechanism	2004	50
Catalytic Properties of Hairpin Ribozymes Derived from Chicory Yellow Mottle Virus and Arabis Mosaic Virus Satellite RNAs Mary Beth DeYoung, Andrew Siwkowski, Ying Lian, Biochemistry	1995	48

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