Josh G. Nichols

Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages

Michael T. Migawa, Guillermo Vasquez, Heather Murray et al. · Nucleic Acids Research · 2014 · 129 citations · Full text

Pharmacy, Biochemistry, Chemistry +16

Binding and Cleavage Specificities of Human Argonaute2

Walt F. Lima, Hongjiang Wu, Josh G. Nichols et al. · Journal of Biological Chemistry · 2009 · 127 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +7

Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

Timothy A. Vickers, Walt F. Lima, Josh G. Nichols et al. · Nucleic Acids Research · 2007 · 94 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Human RNase H1 Discriminates between Subtle Variations in the Structure of the Heteroduplex Substrate

Walt F. Lima, J. Bart Rose, Josh G. Nichols et al. · Molecular Pharmacology · 2006 · 89 citations

Life Sciences, Biochemistry, Molecular Biology +17

Structural Requirements at the Catalytic Site of the Heteroduplex Substrate for Human RNase H1 Catalysis

Walt F. Lima, Josh G. Nichols, Hongjiang Wu et al. · Journal of Biological Chemistry · 2004 · 82 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17