Josh G. Nichols

Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages

Wei Wan, Michael T. Migawa, Guillermo Vasquez et al. · Nucleic Acids Research · 2014 · 127 citations · Full text

Biological Activity, Medicinal Chemistry, Bioorganic Chemistry +12

Binding and Cleavage Specificities of Human Argonaute2

Walt F. Lima, Hongjiang Wu, Josh G. Nichols et al. · Journal of Biological Chemistry · 2009 · 124 citations · Full text

Human Argonaute2, Signal Transduction, G Protein-coupled Receptor +7

Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

Timothy A. Vickers, Walt F. Lima, Josh G. Nichols et al. · Nucleic Acids Research · 2007 · 94 citations · Full text

Human RNase H1 Discriminates between Subtle Variations in the Structure of the Heteroduplex Substrate

Walt F. Lima, J. Bart Rose, Josh G. Nichols et al. · Molecular Pharmacology · 2006 · 89 citations

Structural Requirements at the Catalytic Site of the Heteroduplex Substrate for Human RNase H1 Catalysis

Walt F. Lima, Josh G. Nichols, Hongjiang Wu et al. · Journal of Biological Chemistry · 2004 · 81 citations · Full text