Antisense Oligonucleotide Blockade of Tumor Necrosis Factor-α in Two Murine Models of Colitis

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Medicine, Endocrinology, Molecular Biology +17

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

Veterinary Medicine, Immunology, Infectious Diseases +14

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

Life Sciences, Microbiology, Molecular Biology +10

IL-10 inhibits cytokine production by activated macrophages

David Fiorentino, Albert Zlotnik, Tim R. Mosmann et al. · The Journal of Immunology · 1991 · 2.9K citations · Full text

Life Sciences, Immunology, Immunoregulation +16

Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease

Daniel H. Present, Paul Rutgeerts, Stephan Targan et al. · New England Journal of Medicine · 1999 · 2.7K citations · Full text

Medicine, Clinical Sciences, Pharmacotherapy +14