Bruce M. Spiegelman

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha, Cecilia M. Lindgren, Karl‐Fredrik Eriksson et al. · Nature Genetics · 2003 · 10.6K citations

Life Sciences, Endocrinology, Molecular Biology +16

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science · 1993 · 7.5K citations

Medicine, Endocrinology, Molecular Biology +17

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Pontus Boström, Jun Wu, Mark P. Jedrychowski et al. · Nature · 2012 · 4.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

Zhidan Wu, Pere Puigserver, Chen‐Yu Zhang et al. · Cell · 1999 · 4.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell · 1998 · 3.8K citations · Full text

Life Sciences, Molecular Biology, Physiology +16