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Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

Zhidan Wu, Pere Puigserver, Chen‐Yu Zhang, Guillaume Adelmant, Vamsi K. Mootha, Amy E. Troy, Saverio Cinti, Bradford B. Lowell, Richard C. Scarpulla, Bruce M. Spiegelman

Cell · 1999 · 4.1K citations · 35 references

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35

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell · 1998

+4

3.8K citations

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994

+10

3.5K citations

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

Christophe Fleury, Maria Neverova, Sheila Collins et al. · Nature Genetics · 1997

+10

1.6K citations

A role for brown adipose tissue in diet-induced thermogenesis

Nancy J. Rothwell, Michael J. Stock · Nature · 1979

+10

1.6K citations

Mitochondrial transcription factor A is necessary for mtDNA maintance and embryogenesis in mice

Nils‐Göran Larsson, Jianming Wang, Hans Wilhelmsson et al. · Nature Genetics · 1998

+9

1.6K citations