Mitochondrial transcription factor A is necessary for mtDNA maintance and embryogenesis in mice

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

Victor L. J. Tybulewicz, C. Crawford, Peter K. Jackson et al. · Cell · 1991 · 1.3K citations

Knockout Mouse, Developmental Biology, Lymphocyte Development +9

Mitochondrial Genetics: A Paradigm for Aging and Degenerative Diseases?

Douglas C. Wallace · Science · 1992 · 1.3K citations

Degenerative Processes, Alzheimer's Disease, Mitochondrial Biogenesis +14

Targeted oncogene activation by site-specific recombination in transgenic mice.

Merja Lakso, Brian Sauer, B Mosinger et al. · Proceedings of the National Academy of Sciences · 1992 · 690 citations · Full text

Developmental Biology, Transgenic Mouse Models, Reverse Genetics +11

Similarity of Human Mitochondrial Transcription Factor 1 to High Mobility Group Proteins

Melissa A. Parisi, David A. Clayton · Science · 1991 · 540 citations

Transcriptional Regulation, Systems Biology, Mitochondrial Biogenesis +13