Charles Allerson

Fully 2‘-Modified Oligonucleotide Duplexes with Improved in Vitro Potency and Stability Compared to Unmodified Small Interfering RNA

Charles Allerson, Namir Sioufi, Russell Jarres et al. · Journal of Medicinal Chemistry · 2005 · 442 citations

Pharmacy, Chemical Biology, Molecular Biology +17

Iron‐dependent regulation of the divalent metal ion transporter

Hiromi Gunshin, Charles Allerson, Maria Polycarpou‐Schwarz et al. · FEBS Letters · 2001 · 307 citations · Full text

Medicine, Biochemistry, Molecular Biology +17

Positional Effect of Chemical Modifications on Short Interference RNA Activity in Mammalian Cells

Thazha P. Prakash, Charles Allerson, Prasad Dande et al. · Journal of Medicinal Chemistry · 2005 · 282 citations

Life Sciences, Biochemistry, Molecular Biology +15

Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals

Punit P. Seth, Andrew Siwkowski, Charles Allerson et al. · Journal of Medicinal Chemistry · 2008 · 267 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +17

Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease

Edmund C. Lee, Tania Valencia, Charles Allerson et al. · Nature Communications · 2019 · 194 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +17