Namir Sioufi

Fully 2‘-Modified Oligonucleotide Duplexes with Improved in Vitro Potency and Stability Compared to Unmodified Small Interfering RNA

Charles Allerson, Namir Sioufi, Russell Jarres et al. · Journal of Medicinal Chemistry · 2005 · 440 citations

Vitro Potency, Stability Compared, Small Interfering Rna +13

Pharmacokinetic Properties of 2′-O-(2-Methoxyethyl)-Modified Oligonucleotide Analogs in Rats

Richard S. Geary, Tanya Watanabe, L Truong et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 280 citations

Positional Effect of Chemical Modifications on Short Interference RNA Activity in Mammalian Cells

Thazha P. Prakash, Charles Allerson, Prasad Dande et al. · Journal of Medicinal Chemistry · 2005 · 280 citations

Molecular Biology, Sense Strand, Long Non-coding Rna +18

Improving RNA Interference in Mammalian Cells by 4‘-Thio-Modified Small Interfering RNA (siRNA):  Effect on siRNA Activity and Nuclease Stability When Used in Combination with 2‘-<i>O</i>-Alkyl Modifications

Prasad Dande, Thazha P. Prakash, Namir Sioufi et al. · Journal of Medicinal Chemistry · 2006 · 119 citations

2‘-<i>O</i>-[2-(Methylthio)ethyl]-Modified Oligonucleotide:  An Analogue of 2‘-<i>O</i>-[2-(Methoxy)-ethyl]-Modified Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA

Thazha P. Prakash, Muthiah Manoharan, Andrew M. Kawasaki et al. · Biochemistry · 2002 · 34 citations