Andrew M. Kawasaki

Evaluation of 2‘-modified oligonucleotides containing 2‘-deoxy gaps as antisense inhibitors of gene expression

Brett P. Monia, Elena A. Lesnik, C. Gonzalez et al. · Journal of Biological Chemistry · 1993 · 770 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +16

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Andrew M. Kawasaki, Martin D. Casper, Susan M. Freier et al. · Journal of Medicinal Chemistry · 1993 · 436 citations

Life Sciences, Molecular Biology, Bioorthogonal Chemistry +16

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Elena A. Lesnik, Charles J. Guinosso, Andrew M. Kawasaki et al. · Biochemistry · 1993 · 202 citations

Pharmacy, Biochemistry, Molecular Biology +17

Aminooxy Functionalized Oligonucleotides:  Preparation, On-Support Derivatization, and Postsynthetic Attachment to Polymer Support

Harri M. Salo, Pasi Virta, Harri Hakala et al. · Bioconjugate Chemistry · 1999 · 76 citations

Pharmacy, Biochemistry, Biotechnology +13

Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor

Daniel J. Buzard, Sun Hee Kim, Luis Lopez et al. · ACS Medicinal Chemistry Letters · 2014 · 72 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17