Martin D. Casper

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Andrew M. Kawasaki, Martin D. Casper, Susan M. Freier et al. · Journal of Medicinal Chemistry · 1993 · 432 citations

Bioorganic Chemistry, Molecular Biology, Duplex Stability +16

Structure−Activity Relationships of Novel 2-Substituted Quinazoline Antibacterial Agents

Pei‐Pei Kung, Martin D. Casper, Kimberley L. Cook et al. · Journal of Medicinal Chemistry · 1999 · 225 citations

Antibacterial Agents, Antimicrobial Drug Discovery, Compound 22 +14

Allyl Group as a Protecting Group for Internucleotide Phosphate and Thiophosphate Linkages in Oligonucleotide Synthesis:  Facile Oxidation and Deprotection Conditions

Muthiah Manoharan, Yixin Lü, Martin D. Casper et al. · Organic Letters · 2000 · 43 citations

Lead optimization of 4-(dimethylamino)quinazolines, potent and selective antagonists for the melanin-concentrating hormone receptor 1

Kosuke Kanuma, Katsunori Omodera, Mariko Nishiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 35 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +10

Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1

Kosuke Kanuma, Katsunori Omodera, Mariko Nishiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 28 citations · Full text

Drug Target, Biochemistry, Functional Selectivity +7