Kosuke Kanuma

Anxiolytic- and Antidepressant-Like Profile of ATC0065 and ATC0175: Nonpeptidic and Orally Active Melanin-Concentrating Hormone Receptor 1 Antagonists

Shigeyuki Chaki, Takeo Funakoshi, Shiho Hirota-Okuno et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 132 citations · Full text

Identification of 4-amino-2-cyclohexylaminoquinazolines as metabolically stable melanin-concentrating hormone receptor 1 antagonists

Kosuke Kanuma, Katsunori Omodera, Mariko Nishiguchi et al. · Bioorganic & Medicinal Chemistry · 2006 · 35 citations

Biochemistry, Functional Selectivity, Medicine +7

Lead optimization of 4-(dimethylamino)quinazolines, potent and selective antagonists for the melanin-concentrating hormone receptor 1

Kosuke Kanuma, Katsunori Omodera, Mariko Nishiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 35 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +10

Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1

Kosuke Kanuma, Katsunori Omodera, Mariko Nishiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 28 citations · Full text

Drug Target, Biochemistry, Functional Selectivity +7

In vitro and antinociceptive profile of HON0001, an orally active NMDA receptor NR2B subunit antagonist

Sayoko Suetake-Koga, Toshiharu Shimazaki, Kazuaki Takamori et al. · Pharmacology Biochemistry and Behavior · 2006 · 23 citations

Functional Selectivity, Pain Medicine, Medicine +9