Edmund C. Lee

Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer

Erik Kupperman, Edmund C. Lee, Yueying Cao et al. · Cancer Research · 2010 · 493 citations

Medicine, Oncology, Pharmacology +13

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism

Sachin Hajarnis, Ronak Lakhia, Matanel Yheskel et al. · Nature Communications · 2017 · 207 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease

Edmund C. Lee, Tania Valencia, Charles Allerson et al. · Nature Communications · 2019 · 194 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +17

Antitumor Activity of the Investigational Proteasome Inhibitor MLN9708 in Mouse Models of B-cell and Plasma Cell Malignancies

Edmund C. Lee, Michael Fitzgerald, Bret Bannerman et al. · Clinical Cancer Research · 2011 · 106 citations

Medicine, Oncology, Pharmacology +16

PKD1 and PKD2 mRNA cis-inhibition drives polycystic kidney disease progression

Ronak Lakhia, Harini Ramalingam, Chun-Mien Chang et al. · Nature Communications · 2022 · 74 citations · Full text

Medicine, Genetics, Molecular Genetics +13