Michael Fitzgerald

Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer

Erik Kupperman, Edmund C. Lee, Yueying Cao et al. · Cancer Research · 2010 · 493 citations

Medicine, Oncology, Pharmacology +13

Development of a Catalytic Enantioselective Conjugate Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes for the Synthesis of Endothelin-A Antagonist <b>ABT-546</b>. Scope, Mechanism, and Further Application to the Synthesis of the Antidepressant Rolipram

David M. Barnes, Jianguo Ji, Michael G. Fickes et al. · Journal of the American Chemical Society · 2002 · 209 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Mobocertinib (TAK-788): A Targeted Inhibitor of <i>EGFR</i> Exon 20 Insertion Mutants in Non–Small Cell Lung Cancer

Francois Gonzalvez, Sylvie Vincent, Theresa E. Baker et al. · Cancer Discovery · 2021 · 195 citations · Full text

Medicine, Oncology, Pharmacology +15

Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent

Qun Li, Keith W. Woods, Akiyo Claiborne et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 124 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery

Anar Murphy, Michael Fitzgerald, Teresa Ro et al. · The Journal of Cell Biology · 2014 · 107 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17