Concepedia

Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent

Qun Li, Keith W. Woods, Akiyo Claiborne, Stephen L. Gwaltney, Kenneth J. Barr, Gang Liu, Laura Gehrke, R.B. Credo, Hui Yu, Jang Lee,

Bioorganic & Medicinal Chemistry Letters · 2002 · 124 citations · 14 references

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14

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.

Maria Kavallaris, Dennis Yi‐Shin Kuo, Catherine A. Burkhart et al. · Journal of Clinical Investigation · 1997 · 599 citations · Full text

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Synthesis and Structure−Activity Relationships of 2-Pyridones:  A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents

Qun Li, Daniel T. W. Chu, Akiyo Claiborne et al. · Journal of Medicinal Chemistry · 1996 · 75 citations

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An efficient synthesis of florfenicol

Doris P. Schumacher, Jon E. Clark, Bruce L. Murphy et al. · The Journal of Organic Chemistry · 1990 · 73 citations

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A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.

Sajid Khan Tahir, Edward K. Han, B Credo et al. · PubMed · 2001 · 66 citations

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Phase I study of E7010

Kaichiro Yamamoto, Kiichiro Noda, Akinobu Yoshimura et al. · Cancer Chemotherapy and Pharmacology · 1998 · 64 citations

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