Stephen L. Gwaltney

Discovery of Alogliptin:  A Potent, Selective, Bioavailable, and Efficacious Inhibitor of Dipeptidyl Peptidase IV

Jun Feng, Zhiyuan Zhang, Michael B. Wallace et al. · Journal of Medicinal Chemistry · 2007 · 399 citations · Full text

Plasma Dpp-4 Activity, Pharmacotherapy, Chemical Biology +17

Vinyl Sulfonate Esters and Vinyl Sulfonamides:  Potent, Irreversible Inhibitors of Cysteine Proteases

William Roush, Stephen L. Gwaltney, Jianming Cheng et al. · Journal of the American Chemical Society · 1998 · 226 citations

Pharmaceutical Science, Bioorganic Chemistry, Altmetric Attention Score +18

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu et al. · ACS Medicinal Chemistry Letters · 2017 · 183 citations · Full text

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

Conor R. Caffrey, Elizabeth Hansell, Kimberley D. Lucas et al. · Molecular and Biochemical Parasitology · 2001 · 179 citations

Major Cysteine Protease, Biochemistry, Parasitic Protozoa +7

Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV

Zhiyuan Zhang, Michael B. Wallace, Jun Feng et al. · Journal of Medicinal Chemistry · 2010 · 124 citations · Full text

Pharmaceutical Science, Plasma Dpp-4 Activity, Pharmacotherapy +16