Kobina Dufu

Human mRNA Export Machinery Recruited to the 5′ End of mRNA

Hong Cheng, Kobina Dufu, Chung‐Sheng Lee et al. · Cell · 2006 · 468 citations · Full text

Transcriptional Regulation, Protein Expression, Export Machinery +10

<scp>GBT</scp>440 increases haemoglobin oxygen affinity, reduces sickling and prolongs <scp>RBC</scp> half‐life in a murine model of sickle cell disease

Donna Oksenberg, Kobina Dufu, Mira Patel et al. · British Journal of Haematology · 2016 · 232 citations · Full text

Vitro Hbs Polymerization, Immunology, Selective Partitioning +19

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex

Kobina Dufu, Michaela J. Livingstone, Jan Seebacher et al. · Genes & Development · 2010 · 195 citations · Full text

A role for TREX components in the release of spliced mRNA from nuclear speckle domains

Anusha P. Dias, Kobina Dufu, Haixin Lei et al. · Nature Communications · 2010 · 191 citations · Full text

Signal Transduction, Medicine, Natural Sciences +9

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu et al. · ACS Medicinal Chemistry Letters · 2017 · 183 citations · Full text