Donna Oksenberg

A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors

Donna Oksenberg, Scot A. Marsters, Brian F. O’Dowd et al. · Nature · 1992 · 278 citations

Molecular Pharmacology, Rodent 5-Ht1b Receptors, Functional Selectivity +9

<scp>GBT</scp>440 increases haemoglobin oxygen affinity, reduces sickling and prolongs <scp>RBC</scp> half‐life in a murine model of sickle cell disease

Donna Oksenberg, Kobina Dufu, Mira Patel et al. · British Journal of Haematology · 2016 · 232 citations · Full text

Vitro Hbs Polymerization, Immunology, Selective Partitioning +19

Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor

Patricia Andrade‐Gordon, Bruce E. Maryanoff, Claudia K. Derian et al. · Proceedings of the National Academy of Sciences · 1999 · 186 citations · Full text

Tethered-ligand Receptor, Peptide Engineering, Chemical Biology +17

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu et al. · ACS Medicinal Chemistry Letters · 2017 · 183 citations · Full text

Characterization of the human 5-hydroxytryptamine1B receptor.

Hui Jin, Donna Oksenberg, Avi Ashkenazi et al. · Journal of Biological Chemistry · 1992 · 177 citations · Full text

Molecular Pharmacology, Biochemistry, G Protein-coupled Receptor +11