Kenneth J. Barr

Allosteric inhibition of protein tyrosine phosphatase 1B

Christian Wiesmann, Kenneth J. Barr, Jenny Kung et al. · Nature Structural & Molecular Biology · 2004 · 530 citations

Life Sciences, Biochemistry, Molecular Biology +14

Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues:  Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation

Le Wang, Keith W. Woods, Qun Li et al. · Journal of Medicinal Chemistry · 2002 · 421 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor

Justin A. Caravella, Jian Lin, R. Bruce Diebold et al. · Journal of Medicinal Chemistry · 2020 · 144 citations · Full text

Pharmacy, Oncology, Pharmacology +15

Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent

Qun Li, Keith W. Woods, Akiyo Claiborne et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 124 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye

Min Zhong, Thomas R. Gadek, Minna Bui et al. · ACS Medicinal Chemistry Letters · 2012 · 97 citations · Full text

Medicine, Immunology, Ophthalmology +17