Justin A. Caravella

Molecular basis of USP7 inhibition by selective small-molecule inhibitors

A.P. Turnbull, Stephanos Ioannidis, Wojciech Krajewski et al. · Nature · 2017 · 448 citations

Drug Target, Usp7 Inhibition, Medicine +4

The Drosophila Orphan Nuclear Receptor DHR38 Mediates an Atypical Ecdysteroid Signaling Pathway

K.D. Baker, Lisa M. Shewchuk, Tatiana Kozlova et al. · Cell · 2003 · 236 citations · Full text

Developmental Biology, Developmental Genetics, Genetics +4

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064

Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 137 citations · Full text

Naphthoic Acid-based Analogs, Biochemistry, G Protein-coupled Receptor +12

Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor

Justin A. Caravella, Jian Lin, R. Bruce Diebold et al. · Journal of Medicinal Chemistry · 2020 · 132 citations · Full text

FXR agonist activity of conformationally constrained analogs of GW 4064

Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 61 citations · Full text

G Protein-coupled Receptor, Functional Selectivity, Molecular Biology +4