Justin A. Caravella - Concepedia

Author

Justin A. Caravella

GlaxoSmithKline (United States)ORCID

Also Known As

Caravella, Justin A., J. Caravella, J.A. Caravella, Justin A Caravella, Justin A. Caravella, Justin Caravella

Publications

1.6K

Citations

H-Index

Concepts

All Affiliations

GlaxoSmithKline (United States)Research Triangle Park Foundation Forma Therapeutics (United States)University of Oxford Biogen (United States)

About

Justin A. Caravella is an author at GlaxoSmithKline (United States) specializing in medicine, drug discovery, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	1.1K
2	Natural Sciences	6	6	277
3	Biochemistry	4	4	247
4	Biomolecular Engineering	2	2	44
5	Cell Biology	1	1	43

Justin A. Caravella

Publications

1.5K

Citations

H-Index

Page 1

	Year	Citations
Molecular basis of USP7 inhibition by selective small-molecule inhibitors A.P. Turnbull, Stephanos Ioannidis, Wojciech Krajewski, Nature Drug TargetUsp7 InhibitionMedicineRational Drug DesignPharmacology	2017	448
The Drosophila Orphan Nuclear Receptor DHR38 Mediates an Atypical Ecdysteroid Signaling Pathway K.D. Baker, Lisa M. Shewchuk, Tatiana Kozlova, Cell Developmental BiologyDevelopmental GeneticsGeneticsHormonal ReceptorMolecular Genetics	2003	236
Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064 Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell, Bioorganic & Medicinal Chemistry Letters Naphthoic Acid-based AnalogsBiochemistryG Protein-coupled ReceptorMedicineNatural Sciences	2008	137
Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor Justin A. Caravella, Jian Lin, R. Bruce Diebold, Journal of Medicinal Chemistry	2020	132
FXR agonist activity of conformationally constrained analogs of GW 4064 Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell, Bioorganic & Medicinal Chemistry Letters G Protein-coupled ReceptorFunctional SelectivityMolecular BiologyConformational StudyFxr Agonist Activity	2009	61
Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene Jonathan Y. Bass, Justin A. Caravella, Lihong Chen, Bioorganic & Medicinal Chemistry Letters Drug TargetFunctional SelectivityMedicineHeteroaryl ReplacementsFarnesoid X Receptor	2010	60
Discovery of Substituted Maleimides as Liver X Receptor Agonists and Determination of a Ligand-Bound Crystal Structure Michael Jaye, John A. Krawiec, Nino Campobasso, Journal of Medicinal Chemistry	2005	56
Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064 Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyBiochemistryFunctional SelectivityMedicineReceptor (Biochemistry)	2009	55
Structure-Guided Design of <i>N</i>-Phenyl Tertiary Amines as Transrepression-Selective Liver X Receptor Modulators with Anti-Inflammatory Activity Esther Y. Chao, Justin A. Caravella, Mike Watson, Journal of Medicinal Chemistry	2008	49
Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors Jian Lin, Wei Lu, Justin A. Caravella, Journal of Medicinal Chemistry	2019	46

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