Stephanos Ioannidis

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann et al. · Cancer Cell · 2009 · 526 citations · Full text

Tumor Biology, Signaling Pathway, Solid Tumors +8

Molecular basis of USP7 inhibition by selective small-molecule inhibitors

A.P. Turnbull, Stephanos Ioannidis, Wojciech Krajewski et al. · Nature · 2017 · 448 citations

Drug Target, Usp7 Inhibition, Medicine +4

USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation

Emma V. Rusilowicz-Jones, Jane Jardine, Andreas Kallinos et al. · Life Science Alliance · 2020 · 124 citations · Full text

Mitophagy, Trigger Threshold, Molecular Biology +19

Discovery of 5-Chloro-<i>N</i>²-[(1<i>S</i>)-1-(5-fluoropyrimidin-2-yl)ethyl]-<i>N</i>⁴-(5-methyl-1<i>H</i>-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak/Stat Pathway

Stephanos Ioannidis, Michelle L. Lamb, Tao Wang et al. · Journal of Medicinal Chemistry · 2010 · 123 citations · Full text

Novel Inhibitor, Potent Jak2 Inhibitor, Chemical Biology +24

Effects of the JAK2 Inhibitor, AZ960, on Pim/BAD/BCL-xL Survival Signaling in the Human JAK2 V617F Cell Line SET-2

Joseph M. Gozgit, Geraldine Bebernitz, Pankaj Patil et al. · Journal of Biological Chemistry · 2008 · 101 citations · Full text