Geraldine Bebernitz

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann et al. · Cancer Cell · 2009 · 529 citations · Full text

Medicine, Oncology, Pharmacology +9

Discovery of 5-Chloro-<i>N</i>²-[(1<i>S</i>)-1-(5-fluoropyrimidin-2-yl)ethyl]-<i>N</i>⁴-(5-methyl-1<i>H</i>-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak/Stat Pathway

Stephanos Ioannidis, Michelle L. Lamb, Tao Wang et al. · Journal of Medicinal Chemistry · 2010 · 123 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Effects of the JAK2 Inhibitor, AZ960, on Pim/BAD/BCL-xL Survival Signaling in the Human JAK2 V617F Cell Line SET-2

Joseph M. Gozgit, Geraldine Bebernitz, Pankaj Patil et al. · Journal of Biological Chemistry · 2008 · 101 citations · Full text

Life Sciences, Cell Biology, Pharmacotherapy +13

Expression and analysis of the human cytomegalovirus UL80-encoded protease: identification of autoproteolytic sites

E Z Baum, Geraldine Bebernitz, J D Hulmes et al. · Journal of Virology · 1993 · 81 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Discovery of (2<i>R</i>)-<i>N</i>-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1<i>H</i>-indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor

Qibin Su, Erica Banks, Geraldine Bebernitz et al. · Journal of Medicinal Chemistry · 2020 · 60 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15