Concepedia

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann, Joseph M. Gozgit, Anne Schroeder, Adam Sheehy, Ralf Buettner, David A. Proia, Claudia Kowolik, Brian Armstrong,

Cancer Cell · 2009 · 529 citations · 37 references

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37

Stat3 as an Oncogene

Jacqueline Bromberg, Melissa H Wrzeszczynska, Geeta Devgan et al. · Cell · 1999 · 2.8K citations · Full text

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IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei I. Grivennikov, Eliad Karin, Janoš Terzić et al. · Cancer Cell · 2009 · 2.1K citations · Full text

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Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.7K citations · Full text

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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Guilian Niu, Kenneth L. Wright, Mei Huang et al. · Oncogene · 2002 · 1.2K citations

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

Shizuo Akira, Yukihiro Nishio, Masahiro Inoue et al. · Cell · 1994 · 1K citations

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