Michael Hedvat

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann et al. · Cancer Cell · 2009 · 526 citations · Full text

Tumor Biology, Signaling Pathway, Solid Tumors +8

Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to <i>mda</i> -7/IL-24–mediated toxicity

Rupesh Dash, Belal Azab, Bridget A. Quinn et al. · Proceedings of the National Academy of Sciences · 2011 · 123 citations

Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3

Fan Yang, Christine E. Brown, Ralf Buettner et al. · Molecular Cancer Therapeutics · 2010 · 117 citations · Full text

Antiangiogenic and Antimetastatic Activity of JAK Inhibitor AZD1480

Xin Hong, Andreas Herrmann, Karen L. Reckamp et al. · Cancer Research · 2011 · 112 citations · Full text

Pharmacotherapy, Cancer Biology, Tumor Biology +17

Sunitinib Induces Apoptosis and Growth Arrest of Medulloblastoma Tumor Cells by Inhibiting STAT3 and AKT Signaling Pathways

Fan Yang, Veronica Jové, Xin Hong et al. · Molecular Cancer Research · 2010 · 101 citations · Full text