Jenny Kung

Allosteric inhibition of protein tyrosine phosphatase 1B

Christian Wiesmann, Kenneth J. Barr, Jenny Kung et al. · Nature Structural & Molecular Biology · 2004 · 519 citations

Allosteric Inhibition, Signal Transduction, Biochemistry +5

Allosteric Inhibition of PTP1B Activity by Selective Modification of a Non-Active Site Cysteine Residue

Stig K. Hansen, Mark T. Cancilla, Timothy P. Shiau et al. · Biochemistry · 2005 · 73 citations

Allosteric Inhibition, Bioorganic Chemistry, Aldo-keto Reductase +18

Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering

Daniel A. Erlanson, Robert S. McDowell, Molly M. He et al. · Journal of the American Chemical Society · 2003 · 49 citations

Proteinlipid Interaction, Protein Assembly, Molecular Biology +16

N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells

Sarah Jump, Jenny Kung, Richard E. Staub et al. · Biochemical Pharmacology · 2007 · 47 citations

Cell Regulation, Medicine, I3c-specific Regulation +8

1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells

Hanh H. Nguyen, Sergey N. Lavrenov, Shyam N. Sundar et al. · Chemico-Biological Interactions · 2010 · 43 citations

Anti-estrogenic Properties, Breast Oncology, Medicine +7