Shyam N. Sundar

Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression

Jamin A. Willoughby, Shyam N. Sundar, Mark Cheung et al. · Journal of Biological Chemistry · 2008 · 166 citations · Full text

Medicine, Cancer Biology, Oncology +15

Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes

Antony Tin, Shyam N. Sundar, Kalvin Q. Tran et al. · Anti-Cancer Drugs · 2011 · 106 citations

Medicine, Oncology, Pharmacology +15

Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop

Crystal N. Marconett, Shyam N. Sundar, Kevin M. Poindexter et al. · Molecular Biology of the Cell · 2010 · 74 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells

Crystal N. Marconett, Shyam N. Sundar, Min Tseng et al. · Carcinogenesis · 2011 · 63 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

Shyam N. Sundar, Crystal N. Marconett, Victor B. Doan et al. · Carcinogenesis · 2008 · 61 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17