Robert S. McDowell

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

Eric M. Green, Hiroko Wakimoto, Robert L. Anderson et al. · Science · 2016 · 691 citations · Full text

Benzodiazepine Peptidomimetics: Potent Inhibitors of Ras Farnesylation In Animal Cells

Guy L. James, Joseph L. Goldstein, Michael S. Brown et al. · Science · 1993 · 629 citations

Allosteric inhibition of protein tyrosine phosphatase 1B

Christian Wiesmann, Kenneth J. Barr, Jenny Kung et al. · Nature Structural & Molecular Biology · 2004 · 519 citations

Allosteric Inhibition, Signal Transduction, Biochemistry +5

Binding of small molecules to an adaptive protein–protein interface

Michelle R. Arkin, Mike Randal, Warren L. DeLano et al. · Proceedings of the National Academy of Sciences · 2003 · 372 citations · Full text

Discovery of a Potent Small Molecule IL-2 Inhibitor through Fragment Assembly

Andrew C. Braisted, Johan D. Oslob, Warren L. DeLano et al. · Journal of the American Chemical Society · 2003 · 245 citations