Mike Randal

Allosteric inhibition of protein tyrosine phosphatase 1B

Christian Wiesmann, Kenneth J. Barr, Jenny Kung et al. · Nature Structural & Molecular Biology · 2004 · 519 citations

Allosteric Inhibition, Signal Transduction, Biochemistry +5

Site-directed ligand discovery

Daniel A. Erlanson, Andrew C. Braisted, D.R. Raphael et al. · Proceedings of the National Academy of Sciences · 2000 · 461 citations · Full text

Binding of small molecules to an adaptive protein–protein interface

Michelle R. Arkin, Mike Randal, Warren L. DeLano et al. · Proceedings of the National Academy of Sciences · 2003 · 372 citations · Full text

Potent Small-Molecule Binding to a Dynamic Hot Spot on IL-2

Christopher D. Thanos, Mike Randal, James A. Wells · Journal of the American Chemical Society · 2003 · 103 citations

Protein Assembly, Molecular Biology, Chemical Biology +17

Integrating Fragment Assembly and Biophysical Methods in the Chemical Advancement of Small-Molecule Antagonists of IL-2:  An Approach for Inhibiting Protein−Protein Interactions

Brian C. Raimundo, Johan D. Oslob, Andrew C. Braisted et al. · Journal of Medicinal Chemistry · 2004 · 83 citations · Full text

Drug Target, Molecular Biology, Chemical Biology +16