Concepedia

Tubulin Depolymerization Inhibitors

Tubulin Depolymerization Inhibitor is a microtubule-stabilizing agent that suppresses the disassembly of tubulin polymers into monomers, thereby maintaining microtubule integrity and function during mitosis.

345

Publications

15.2K

Citations

2.1K

Authors

538

Institutions

Publications per year

2017–2026

109

Variants

Tubulin Depolymerization Inhibitor

Parents

Publications

345

Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death

Malgorzata Borowiak, Wallis Nahaboo, Martin Reynders et al. · Cell · 2015 · 421 citations · Full text

, , +16

Taxol-induced polymerization of purified tubulin. Mechanism of action.

Nitesh Kumar · Journal of Biological Chemistry · 1981 · 404 citations · Full text

, , +17

Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor Nocodazole

Gary W. Zieve, Deborah Turnbull, J. Michael Mullins et al. · Experimental Cell Research · 1980 · 399 citations

, , +15

Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules.

Gregg G. Gundersen, Sarwar Khawaja, J C Bulinski · The Journal of Cell Biology · 1987 · 304 citations · Full text

, , +14

NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent

Benjamin Nicholson, G. Kenneth Lloyd, Brian Miller et al. · Anti-Cancer Drugs · 2005 · 253 citations

, , +14

1–5 of 345

Authors

2.1K

  1. EH
    Ernest Hamel

    National Cancer Institute, United States

    20 publications · 784 citations

    17

    h-index

  2. ÄK
    Ähmed Kamal

    Indian Institute of Chemical Technology, India

    12 publications · 581 citations

    12

    h-index

  3. DP
    Dulal Panda

    Indian Institute of Technology Bombay, India

    8 publications · 447 citations

    8

    h-index

  4. GV
    Giampietro Viola

    University of Padua, Italy

    7 publications · 156 citations

    7

    h-index

  5. HZ
    Hai‐Liang Zhu

    Nanjing University, China

    6 publications · 129 citations

    6

    h-index

1–5 of 2.1K

Institutions

538

  1. National Cancer Institute

    Bethesda, United States

    17 h-index

    42 publications

    2.3K citations

  2. National Institutes of Health

    Bethesda, United States

    17 h-index

    40 publications

    1.7K citations

  3. Indian Institute of Chemical Technology

    Hyderabad, India

    15 h-index

    95 publications

    4K citations

  4. National Institute of Pharmaceutical Education and Research - Ahmedabad

    Ahmedabad, India

    13 h-index

    55 publications

    2.2K citations

  5. Frederick National Laboratory for Cancer Research

    Frederick, United States

    11 h-index

    14 publications

    404 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    70 publications

    4.7K citations

  7. The University of Tokyo

    Tokyo, Japan

    8 h-index

    30 publications

    799 citations

  8. Inserm

    Paris, France

    8 h-index

    48 publications

    1.5K citations

1–8 of 538

Venues

  1. European Journal of Medicinal Chemistry

    45 publications · 1.7K citations

    27

    h-index

  2. Bioorganic & Medicinal Chemistry

    37 publications · 1.6K citations

    27

    h-index

  3. Bioorganic & Medicinal Chemistry Letters

    22 publications · 880 citations

    17

    h-index

  4. Bioorganic Chemistry

    19 publications · 745 citations

    16

    h-index

  5. PubMed

    Repository · 12 publications · 701 citations

    12

    h-index

1–5