Edward K. Han

ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

Cherrie K. Donawho, Yan Luo, Yanping Luo et al. · Clinical Cancer Research · 2007 · 773 citations · Full text

Medicine, Oncology, Pharmacology +15

Potent and selective inhibitors of Akt kinases slow the progress of tumors <i>in vivo</i>

Yan Luo, Alexander R. Shoemaker, Xuesong Liu et al. · Molecular Cancer Therapeutics · 2005 · 244 citations · Full text

Medicine, Oncology, Pharmacology +15

Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines

Jin T. E. Lim, Gary A. Piazza, Edward K. Han et al. · Biochemical Pharmacology · 1999 · 210 citations

Medicine, Oncology, Pharmacology +8

PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.

Angela Cacace, Marius Ueffing, Alex Philipp et al. · PubMed · 1996 · 157 citations

Life Sciences, Cell Biology, Molecular Biology +14

Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis.

Edward K. Han, Martin Begemann, Alessandro Sgambato et al. · PubMed · 1996 · 143 citations

Life Sciences, Cell Biology, Oncology +17